Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL589560 | 0.82 | SCN10A (0.70) | SCN10AALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL5100681 | 0.81 | ALDH1A1 (0.57) | SCN10AALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL580877 | 0.81 | ALDH1A1 (0.57) | SCN10AALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL11740622 | 0.81 | ALDH1A1 (0.61) | SCN10AALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL10749817 | 0.76 | ALDH1A1 (0.59) | ALDH1A1HTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL15996322 | 0.73 | SCN10A (0.54) | SCN10AALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL4067157 | 0.73 | CYP1A2 (0.57) | SCN10AALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL5104200 | 0.73 | SCN10A (0.43) | SCN10AALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL589667 | 0.71 | CYP1A2 (0.49) | SCN10AALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL5100663 | 0.70 | ALDH1A1 (0.54) | SCN10AALDH1A1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847543-A1 | Dihydrothienopyrimidines for the treatment of inflammatory diseases | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2007-10-24 | — | — | EP | disclosed |