Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 6/20 | 0.32 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 2/20 | 0.30 |
| ▸ | HRH1 | P35367 | 2/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460098 | 0.94 | REN (0.38) | RENRORCHRH2HRH1 | |
| SCHEMBL4582501 | 0.92 | REN (0.37) | RENRORCTHRBSLC6A4HRH3 | |
| SCHEMBL8471522 | 0.92 | REN (0.37) | RENRORCTHRBSLC6A4HRH3 | |
| SCHEMBL4582496 | 0.92 | REN (0.37) | RENRORCTHRBSLC6A4HRH3 | |
| SCHEMBL8471475 | 0.90 | REN (0.37) | RENRORCTHRBALDH1A1CYP3A4 | |
| SCHEMBL8468981 | 0.89 | REN (0.33) | RENSLC6A4HRH3CYP3A4CYP2D6 | |
| SCHEMBL8458766 | 0.89 | REN (0.43) | RENCYP3A4 | |
| SCHEMBL4582751 | 0.87 | REN (0.36) | RENRORCSLC6A4HRH3PIK3CD | |
| SCHEMBL4582750 | 0.87 | REN (0.36) | RENRORCSLC6A4HRH3PIK3CD | |
| SCHEMBL8469312 | 0.87 | REN (0.36) | RENRORCTHRBSLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-1908761-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |