Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5106389 | 0.85 | KDM4E (0.53) | ALDH1A1KDM4EL3MBTL1NPSR1KMT2A | |
| SCHEMBL17206259 | 0.84 | KDM4E (0.52) | ALDH1A1KDM4EL3MBTL1NPSR1KMT2A | |
| SCHEMBL8473546 | 0.84 | CHRM3 (0.46) | ALDH1A1KDM4EL3MBTL1NPSR1KMT2A | |
| SCHEMBL14447514 | 0.80 | TACR1 (0.64) | ALDH1A1KDM4EKMT2AMAPTTACR1 | |
| SCHEMBL1663014 | 0.78 | AKR1C3 (0.60) | KDM4ENPSR1KMT2AMEN1 | |
| SCHEMBL4013508 | 0.78 | GAA (0.56) | KDM4ENPSR1KMT2AGAAMAPT | |
| SCHEMBL5226002 | 0.77 | TDP1 (0.54) | KDM4ENPSR1KMT2AGAAMAPT | |
| SCHEMBL18415466 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EL3MBTL1NPSR1KMT2A | |
| SCHEMBL16438566 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EL3MBTL1NPSR1KMT2A | |
| SCHEMBL30076369 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4ENPSR1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948817-A | Polycyclic ethyl alkylamide melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1998038991-A1 | POLYCYCLIC ETHYL ALKYLAMIDE MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |