Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1299560 | 0.84 | HPGD (0.64) | HPGDNPC1RAB9ASMN1; SMN2ACACB | |
| SCHEMBL4122451 | 0.79 | HPGD (0.58) | HPGDNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6072643 | 0.79 | SMN1; SMN2 (0.56) | HPGDNPC1RAB9ASMN1; SMN2ACACB | |
| SCHEMBL3019071 | 0.79 | RAB9A (0.56) | HPGDNPC1RAB9ASMN1; SMN2ACACB | |
| SCHEMBL13849692 | 0.78 | NPC1 (0.52) | HPGDNPC1RAB9ASMN1; SMN2ACACB | |
| SCHEMBL30611110 | 0.78 | RAB9A (0.55) | HPGDNPC1RAB9ASMN1; SMN2ACACB | |
| SCHEMBL19599017 | 0.78 | NPC1 (0.52) | HPGDNPC1RAB9ASMN1; SMN2ACACB | |
| SCHEMBL3394710 | 0.78 | MEN1 (0.42) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL26454425 | 0.78 | NPC1 (0.55) | HPGDNPC1RAB9ASMN1; SMN2ACACB | |
| SCHEMBL1390600 | 0.78 | NPC1 (0.55) | HPGDNPC1RAB9ASMN1; SMN2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007693-A1 | BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |