SCHEMBL8472483

SCHEMBL8472483

CCCCc1ccc(-c2c([O])cc(F)c(CCc3cc(F)c(OC(F)(F)F)c(F)c3)c2F)c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.32
PCSK9 Q8NBP7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8476679 0.97 RARB (0.35) RARB
SCHEMBL8473521 0.94 PDK2 (0.31)
SCHEMBL8472687 0.91 FFAR4 (0.32)
SCHEMBL8471174 0.89 FFAR4 (0.35) RARBPCSK9
SCHEMBL8472246 0.88
SCHEMBL8473838 0.87 RARB (0.36) RARB
SCHEMBL8473755 0.86 DAO (0.34) RARB
SCHEMBL8471611 0.86 RARB (0.32) RARB
SCHEMBL8472885 0.86 RARB (0.38) RARB
SCHEMBL8473305 0.85 PTGS2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5858270-A Difluorooxymethane derivative and liquid crystal composition CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed