Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | GBA1 | P04062 | 3/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.51 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.51 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.51 |
| ▸ | GJB2 | P29033 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25415166 | 0.92 | MAPK1 (0.60) | MAPK1GBA1SLC2A1LGALS8LGALS3 | |
| SCHEMBL25415432 | 0.92 | MAPK1 (0.60) | MAPK1GBA1SLC2A1LGALS8LGALS3 | |
| SCHEMBL25414516 | 0.92 | MAPK1 (0.60) | MAPK1GBA1SLC2A1LGALS8LGALS3 | |
| SCHEMBL5678760 | 0.91 | MAPK1 (0.58) | MAPK1GBA1SLC2A1LGALS8LGALS3 | |
| SCHEMBL28652350 | 0.89 | MAPK1 (0.64) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL8864271 | 0.89 | MAPK1 (0.64) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL7715117 | 0.89 | MAPK1 (0.64) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL8864174 | 0.89 | MAPK1 (0.64) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL7711399 | 0.89 | MAPK1 (0.64) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL28196084 | 0.89 | MAPK1 (0.64) | MAPK1GBA1LGALS8LGALS3LGALS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869460-A | ANTIINFLAMMATORY AGENTS | SANWA KAGUKU KENKYUSHO CO., LTD. (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0771815-A1 | Sulfated and phosphated saccharide derivatives, process for the preparation of the same and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1997-05-07 | — | — | EP | disclosed |