Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596509 | 0.93 | KDM4E (0.50) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL1770853 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL30280995 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL2318882 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL1720999 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL18420521 | 0.83 | NOTUM (0.45) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL31385726 | 0.83 | NOTUM (0.45) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL2897750 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL274700 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL5417457 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1GAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856344-A | CARDIOVASCULAR DISORDERS; ANTIARRHYTHMIA AGENTS; CENTRAL NERVOUS SYSTEM DISORDERS; STOCK | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-01-05 | — | — | US | disclosed |