Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CFTR | P13569 | 3/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318882 | 1.00 | KDM4E (0.55) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL274700 | 0.92 | KDM4E (0.55) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL5417457 | 0.90 | KDM4E (0.53) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL1720999 | 0.90 | KDM4E (0.56) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL2811951 | 0.90 | KDM4E (0.53) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL2897750 | 0.88 | KDM4E (0.61) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL8473587 | 0.87 | KDM4E (0.50) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL3187202 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL1770853 | 0.85 | KDM4E (0.49) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL2242907 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1GAAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |