Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475112 | 1.00 | TDP1 (0.54) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL8334285 | 0.87 | ALDH1A1 (0.54) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL8474228 | 0.86 | ALDH1A1 (0.52) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL8475810 | 0.82 | ALDH1A1 (0.65) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL8471464 | 0.82 | ALDH1A1 (0.65) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL8799111 | 0.77 | TDP1 (0.54) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL8799115 | 0.77 | TDP1 (0.54) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL14866021 | 0.75 | TDP1 (0.58) | TDP1ALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL8272228 | 0.75 | TSHR (0.51) | ALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL2246856 | 0.75 | TSHR (0.51) | ALDH1A1KMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919949-A | α-hydroxy acid esters useful as intermediates in the production of β-amino alcohols | HOFFMANN-LA ROCHE INC. (US) | 1999-07-06 | — | — | US | claimed |