SCHEMBL847407

SCHEMBL847407

Nc1ccsc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL19874510 0.97
SCHEMBL6873402 0.69 CYP2A6 (0.42)
SCHEMBL3715393 0.69 CES1 (0.39)
SCHEMBL414468 0.69
SCHEMBL2304249 0.69
SCHEMBL225071 0.69
SCHEMBL20273158 0.67
Hydrochloric Acid SCHEMBL6193713 0.67
SCHEMBL7998906 0.67
SCHEMBL18985992 0.67 TDP1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101453895-B Insecticidal methods using 4-amino-5-chloro-thieno[2,3-d]-pyrimidine compounds MERIAL LTD 2012-09-05 CN claimed
CN-101453895-A Insecticidal methods using 4-amino-5-chloro-thieno[2,3-d]-pyrimidine compounds BASF SE (DE) 2009-06-10 CN claimed
US-7297168-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-11-20 US claimed
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-15 US claimed
WO-2026103888-A1 PYRIMIDIN-2(1H)-ONE DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 上海青润医药科技有限公司 2026-05-21 WO disclosed
CN-122036626-A Pyrimidine-2 (1H) -ketone derivative, pharmaceutical composition and application thereof 上海青润医药科技有限公司 2026-05-15 CN disclosed
US-20250101015-A1 HETEROCYCLIC KINASE INHIBITORS AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2025-03-27 US disclosed
US-20250084076-A1 HETEROCYCLIC KINASE INHIBITORS AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2025-03-13 US disclosed
US-12172993-B2 Heterocyclic kinase inhibitors and uses thereof IOMX THERAPEUTICS AG (DE) 2024-12-24 US disclosed
US-20210387982-A1 HETEROCYCLIC KINASE INHIBITORS AND USES THEREOF IOMX THERAPEUTICS AG (DE) 2021-12-16 US disclosed
US-11180470-B2 Herbicidal pyrimidine compounds BASF SE (DE) 2021-11-23 US disclosed
CN-112955447-A Heterocyclic kinase inhibitors and uses thereof 艾欧麦克斯治疗股份公司 2021-06-11 CN disclosed
US-20060014794-A1 CXCR1 and CXCR2 chemokine antagonists SCHERING CORPORATION 2006-01-19 US disclosed
WO-2005113534-A2 CXCR1 AND CXCR2 CHEMOKINE ANTAGONISTS SCHERING CORPORATION (US) 2005-12-01 WO disclosed
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-15 US disclosed
WO-2005074875-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-08-18 WO disclosed
US-20050148775-A1 Process for production of heteroaryl-type boron compounds with iridium catalyst MITSUBISHI RAYON CO., LTD. (JP) 2005-07-07 US disclosed
EP-1481978-A1 PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST Mitsubishi Rayon Co., Ltd. (JP) 2004-12-01 EP disclosed
US-4263205-A FOR COLORING POLYMERS, LACQUERS CIBA-GEIGY CORPORATION (US) 1981-04-21 US disclosed
EP-0006154-A1 Monoazo pigments and their use in colouring high molecular-weight organic material CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed