⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6193713 | 0.97 | — | — | |
| Propane SCHEMBL652956 | 0.89 | ALDH1A1 (0.38) | — | |
| SCHEMBL3715393 | 0.80 | CES1 (0.39) | — | |
| SCHEMBL7135863 | 0.75 | CES1 (0.36) | — | |
| SCHEMBL7998906 | 0.71 | — | — | |
| SCHEMBL20273158 | 0.71 | — | — | |
| SCHEMBL3345266 | 0.69 | — | — | |
| SCHEMBL847406 | 0.69 | — | — | |
| SCHEMBL847407 | 0.69 | — | — | |
| SCHEMBL8287305 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209449-B | Inhibitors of the kynurenine pathway | 库拉德夫制药私人有限公司 | 2019-02-01 | — | — | CN | claimed |
| US-20180105668-A1 | METHODS OF ISOLATING MELT-PROCESSIBLE POLYCARBONATE FROM PLASTIC WASTE, METHODS OF PREPARING POLYCARBONATE-CONTAINING HYBRID POLYMERS, AND COMPOSITIONS COMPRISING SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2018-04-19 | — | — | US | claimed |
| EP-3116935-A1 | NOVEL COVALENTLY CROSS-LINKED MALLEABLE POLYMERS AND METHODS OF USE | The Regents of the University of Colorado, a body corporate (US) | 2017-01-18 | — | — | EP | claimed |
| CN-105209449-A | Inhibitors of the kynurenine pathway | CURADEV PHARMA PRIVATE LTD | 2015-12-30 | — | — | CN | claimed |
| WO-2015138804-A1 | NOVEL COVALENTLY CROSS-LINKED MALLEABLE POLYMERS AND METHODS OF USE | THE REGENTS OF THE UNIVERITY OF COLORADO, A BODY CORPORATE (US) | 2015-09-17 | — | — | WO | claimed |
| CN-103601996-B | The preparation method of the compound hollow-particle of a kind of monodisperse polystyrene/conducting polymer | NANJING UNIVERSITY (CN) | 2015-09-02 | — | — | CN | claimed |
| CN-103601996-A | Method for preparing monodisperse polystyrene/conductive macromolecular composite hollow particles | NANJING UNIVERSITY OF TECHNOLOGY | 2014-02-26 | — | — | CN | claimed |
| WO-2012076966-A1 | SUBSTITUTED THIENO [3,4-B] PYRAZINE COMPOUNDS | LUPIN LIMITED (IN) | 2012-06-14 | — | — | WO | claimed |
| CN-100540554-C | Novel compounds capable of being used in organic layers of organic light emitting devices | LG CHEMICAL LTD (KR) | 2009-09-16 | — | — | CN | claimed |
| WO-2009097490-A1 | 1H-PYRAZOLO[3,4-D]PYRIMIDINE, PURINE, 7H-PURIN-8(9H)-ONE, 3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE, AND THIENO[3,2-D]PYRIMIDINE COMPOUNDS, THEIR USE AS mTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH (US) | 2009-08-06 | — | — | WO | claimed |
| US-5807879-A | Biotinidase-resistant biotinylated compound and methods of use thereof | UNIVERSITY OF ROCHESTER (US) | 1998-09-15 | — | — | US | claimed |
| US-5776894-A | Chelated somatostatin peptides and complexes thereof, pharmaceutical compositions containing them and their use in treating tumors | NOVARTIS AG (CH) | 1998-07-07 | — | — | US | claimed |
| WO-1998028336-A1 | POLYSACCHARIDE-PEPTIDE DERIVATIVES | MAP MEDICAL TECHNOLOGIES OY (FI) | 1998-07-02 | — | — | WO | claimed |
| US-5753627-A | Use of certain complexed somatostatin peptides for the invivo imaging of somatostatin receptor-positive tumors and metastasis | NOVARTIS AG (CH) | 1998-05-19 | — | — | US | claimed |
| WO-1998014219-A2 | A METHOD FOR THE REDUCTION OF OXYGENATED COMPOUNDS OF RHENIUM OR TECHNETIUM | NYCOMED AMERSHAM SORIN S.R.L. (IT) | 1998-04-09 | — | — | WO | claimed |
| US-5262175-A | Containing technetium by addition of an oxidizing agent | SOLANKI KISHOR K (GB) | 1993-11-16 | — | — | US | claimed |
| EP-0258855-B1 | PROCESS FOR THE PREPARATION OF AMINOTHIOPHENE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1992-02-12 | — | — | EP | claimed |
| US-5064962-A | DIAMINOTHIOPHENES | BASF AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | claimed |
| EP-0384314-A2 | Diaminothiophenes | BASF Aktiengesellschaft (DE) | 1990-08-29 | — | — | EP | claimed |
| WO-1990006949-A2 | PEPTIDE DERIVATIVES | SANDOZ AG (CH) | 1990-06-28 | — | — | WO | claimed |