Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052775 | 0.74 | TNKS2 (0.39) | MAPTSMN1; SMN2LMNARAB9AMEN1 | |
| SCHEMBL6052867 | 0.73 | PTPRC (0.35) | TDP1MAPTSMN1; SMN2TP53CYP1A2 | |
| SCHEMBL11481627 | 0.72 | BCHE (0.44) | TDP1MAPTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL11481881 | 0.70 | CDC25B (0.41) | TDP1MAPTSMN1; SMN2TP53CYP1A2 | |
| SCHEMBL11481892 | 0.68 | RET (0.37) | TDP1MAPTSMN1; SMN2TP53CYP1A2 | |
| SCHEMBL14364127 | 0.66 | HTT (0.35) | TDP1KDM4EPPARGHTTMAPK1 | |
| SCHEMBL16708761 | 0.65 | ALDH1A1 (0.40) | MAPTTP53SLC25A5POLBMEN1 | |
| SCHEMBL17395714 | 0.65 | GAA (0.62) | TDP1MAPTSMN1; SMN2TP53CYP1A2 | |
| SCHEMBL5036828 | 0.65 | RET (0.41) | TDP1SMN1; SMN2TP53KDM4ELMNA | |
| SCHEMBL11493735 | 0.64 | CDC25B (0.46) | TDP1MAPTSMN1; SMN2TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977187-A | 4-substituted-1,2-naphthoquinones and their use in the inhibition of neoplastic cell growth | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-11-02 | — | — | US | disclosed |