SCHEMBL8474976

SCHEMBL8474976

COC1CCC(C)C(OC)C1OC

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.32
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11011441 0.92 APLNR (0.33) APLNRCYP2D6
SCHEMBL8230622 0.80
SCHEMBL26176593 0.77
SCHEMBL5044748 0.77
SCHEMBL12860105 0.77
SCHEMBL13367601 0.77
SCHEMBL10985851 0.77 CYP2D6 (0.37) CYP2D6
SCHEMBL10990099 0.76 APLNR (0.33) APLNRCYP2D6
SCHEMBL24104270 0.72
SCHEMBL8227584 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1277741-A1 CYCLIC COMPOUNDS TANABE SEIYAKU CO., LTD. (JP) 2003-01-22 EP disclosed
US-4497815-A 1-(N-Substituted carbamoyl)-5-fluorouracil derivatives and the carcinostatic agents containing same as active ingredients Ozaki, Shoichiro (JP) 1985-02-05 US disclosed