Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.38 |
| ▸ | PDE4A | P27815 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479901 | 0.89 | — | — | |
| SCHEMBL8475575 | 0.88 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8475695 | 0.88 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8474810 | 0.87 | MAPT (0.37) | — | |
| SCHEMBL8477805 | 0.85 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8481067 | 0.83 | GCGR (0.33) | ALDH1A1 | |
| SCHEMBL8478650 | 0.83 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8479393 | 0.79 | PDE4B (0.51) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8480648 | 0.79 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8482102 | 0.78 | GCGR (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |