SCHEMBL8482102

SCHEMBL8482102

CCCc1[c]c(-c2ccc(C)cc2)c(OC)c(-c2ccc(C)cc2)c1OC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.32
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8479901 0.90
SCHEMBL8480989 0.88 DPP4 (0.32) ALDH1A1GAASMN1; SMN2
SCHEMBL8474773 0.88 MAPT (0.38) ALDH1A1GAA
SCHEMBL8474660 0.87 PTGS2 (0.33) GCGRALDH1A1GAA
SCHEMBL8475575 0.87 PDE4B (0.44)
SCHEMBL8474097 0.85 MGAM (0.41) GAA
SCHEMBL8477575 0.85 PDE4B (0.40) GAA
SCHEMBL8481466 0.82 PDE4B (0.36) GAA
SCHEMBL8474810 0.80 MAPT (0.37) GAA
SCHEMBL8581095 0.80 MAPK1 (0.36) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6004988-A Carboxylic acid derivatives, their preparation and their use BASF AKTIENGESELLSCHAFT (DE) 1999-12-21 US disclosed