Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334459 | 0.84 | ALDH1A1 (0.35) | ALDH1A1ALOX15 | |
| SCHEMBL14024890 | 0.76 | ALDH1A1 (0.35) | ALDH1A1ALOX15 | |
| SCHEMBL16136558 | 0.69 | — | — | |
| SCHEMBL42869 | 0.69 | — | — | |
| SCHEMBL13595177 | 0.68 | — | — | |
| SCHEMBL10139309 | 0.68 | — | — | |
| SCHEMBL12597887 | 0.68 | — | — | |
| SCHEMBL10433083 | 0.68 | — | — | |
| SCHEMBL17460637 | 0.65 | — | — | |
| SCHEMBL1998894 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986131-A | UNSATURATED CARBOXYLIC ACID DERIVATIVES AS LIGANDS AND RETINOIC ACID RECEPTORS | HOFFMANN-LA ROCHE INC. (US) | 1999-11-16 | — | — | US | disclosed |
| EP-0728742-A2 | Novel retinoids | F. HOFFMANN-LA ROCHE AG (CH) | 1996-08-28 | — | — | EP | disclosed |