Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475256 | 0.90 | L3MBTL1 (0.40) | MAPTMAPK1TDP1L3MBTL1GAA | |
| SCHEMBL8479563 | 0.89 | CYP4F2 (0.42) | MAPTMAPK1TDP1L3MBTL1GAA | |
| SCHEMBL8480765 | 0.86 | MGAM (0.41) | GAAMGAMSIMGAM2BCHE | |
| SCHEMBL8474508 | 0.83 | CYP4F2 (0.39) | MAPTMAPK1TDP1L3MBTL1GAA | |
| SCHEMBL8477547 | 0.82 | L3MBTL1 (0.42) | MAPTMAPK1TDP1L3MBTL1GAA | |
| SCHEMBL8474826 | 0.82 | MGAM (0.41) | GAAMGAMSIMGAM2IKBKE | |
| SCHEMBL8478626 | 0.81 | MGAM (0.41) | GAAMGAMSIMGAM2BCHE | |
| SCHEMBL8475020 | 0.81 | NPSR1 (0.40) | MAPTMAPK1GAAPOLBLMNA | |
| SCHEMBL8480711 | 0.78 | MGAM (0.43) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL8474097 | 0.77 | MGAM (0.41) | GAAMGAMSIMGAM2IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |