Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479483 | 0.91 | GAA (0.52) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL8480505 | 0.85 | GAA (0.53) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL8478141 | 0.83 | GAA (0.49) | GAAMAPTTP53GLACDK1 | |
| Sulfosulfuron SCHEMBL66574 | 0.83 | GAA (0.49) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL55236 | 0.82 | GAA (0.52) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL8477231 | 0.82 | GAA (0.52) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL8535700 | 0.82 | GAA (0.52) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL8477647 | 0.82 | GAA (0.57) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL8478329 | 0.82 | GAA (0.48) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL8480476 | 0.81 | GAA (0.50) | GAAMAPTTP53GLACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990048-A | METRIBUZIN AND SULFOSULFURON (2-ETHYLSULFONYL-N-(((4,6-DIMETHOXY-PYRIMIDIN-2 -YL)AMINO)CARBONYL)IMIDAZO(1,2-A)PYRIDINE-3-SULFONAMIDE) ACT SYNERGISTICALLY AT SPECIFIC WEIGHT RATIOS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | disclosed |