Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL55236 | 1.00 | GAA (0.52) | GAARAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL9362781 | 0.94 | GAA (0.46) | GAARAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL12633039 | 0.94 | GAA (0.46) | GAARAB9ASMN1; SMN2MAPK1MAPT | |
| Halosulfuron SCHEMBL3374072 | 0.91 | GAA (0.44) | GAARAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL9517874 | 0.89 | MAPT (0.45) | GAARAB9ASMN1; SMN2MAPK1MAPT | |
| SCHEMBL8480505 | 0.89 | GAA (0.53) | GAAMAPTALDH1A1TP53GLA | |
| SCHEMBL8477231 | 0.88 | GAA (0.52) | GAAMAPTALDH1A1TP53GLA | |
| SCHEMBL8477647 | 0.88 | GAA (0.57) | GAASMN1; SMN2MAPTALDH1A1TP53 | |
| SCHEMBL5904842 | 0.86 | RAB9A (0.46) | GAARAB9ASMN1; SMN2MAPK1MAPT | |
| Dichlormid SCHEMBL2373458 | 0.86 | GAA (0.40) | GAARAB9ASMN1; SMN2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |