Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223353 | 0.77 | GAA (0.43) | GAAALDH1A1LMNAHSD17B10FDPS | |
| SCHEMBL21542085 | 0.76 | GAA (0.46) | GAAALDH1A1LMNAHSD17B10 | |
| SCHEMBL27333779 | 0.72 | ALDH1A1 (0.40) | GAAALDH1A1LMNAHSD17B10FDPS | |
| SCHEMBL21542093 | 0.72 | GAA (0.43) | GAAALDH1A1LMNAHSD17B10FDPS | |
| SCHEMBL28349840 | 0.72 | GAA (0.46) | GAAALDH1A1LMNAHSD17B10FDPS | |
| SCHEMBL12776902 | 0.72 | GAA (0.46) | GAAALDH1A1LMNAHSD17B10FDPS | |
| SCHEMBL11657611 | 0.71 | TSHR (0.37) | GAAALDH1A1 | |
| SCHEMBL12776904 | 0.70 | GAA (0.50) | GAAALDH1A1LMNAHSD17B10FDPS | |
| SCHEMBL1579162 | 0.70 | GAA (0.50) | GAAALDH1A1LMNAHSD17B10FDPS | |
| SCHEMBL11659516 | 0.70 | TSHR (0.38) | GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004954-A | TREATING GRAFT-VERSUS-HOST DISEASE AND AUTOIMMUNE DISEASES; ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-21 | — | — | US | disclosed |