Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 3/20 | 0.53 |
| ▸ | CES1 | P23141 | 3/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11867860 | 0.87 | CES2 (0.61) | MEN1KMT2ACES2CES1EPHX2 | |
| SCHEMBL3419748 | 0.87 | CES2 (0.61) | MEN1KMT2ACES2CES1EPHX2 | |
| SCHEMBL817804 | 0.87 | CES2 (0.61) | MEN1KMT2ACES2CES1EPHX2 | |
| SCHEMBL16703140 | 0.87 | CES2 (0.61) | MEN1KMT2ACES2CES1EPHX2 | |
| SCHEMBL10354085 | 0.87 | CES2 (0.61) | MEN1KMT2ACES2CES1EPHX2 | |
| SCHEMBL11595706 | 0.87 | CES2 (0.61) | MEN1KMT2ACES2CES1EPHX2 | |
| SCHEMBL11497473 | 0.85 | CES2 (0.59) | CES2CES1EPHX2PTGS2NAAA | |
| SCHEMBL8994830 | 0.85 | CES2 (0.47) | MEN1KMT2ACES2CES1TP53 | |
| SCHEMBL816950 | 0.85 | CES2 (0.59) | CES2CES1EPHX2PTGS2NAAA | |
| SCHEMBL1000399 | 0.84 | KCNH2 (0.54) | MEN1KMT2ACES2CES1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5964692-A | Functional fluids and liquid cleaning compositions and suspending media | ALBRIGHT & WILSON LIMITED (GB) | 1999-10-12 | — | — | US | disclosed |
| US-5807810-A | SURFACTANT MIXTURE | ALBRIGHT & WILSON LIMITED (GB) | 1998-09-15 | — | — | US | disclosed |