SCHEMBL8475723

SCHEMBL8475723

Cc1csc2c1NC(NC(C)C)=NS2(=O)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7078037 0.84
SCHEMBL7077929 0.84 CXCR2 (0.31)
SCHEMBL8475613 0.83
SCHEMBL8474127 0.80 PDE4B (0.34)
SCHEMBL8473769 0.79 HPGD (0.36)
SCHEMBL7078936 0.77
SCHEMBL8476792 0.75 ELANE (0.31)
SCHEMBL8474564 0.75
SCHEMBL7073682 0.73 NT5E (0.30)
SCHEMBL7079890 0.73 NT5E (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1158290-C Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use ŵ��Ų�ڿ˹�˾ 2004-07-21 CN disclosed
US-5889002-A CENTRAL NERVOUS SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS; GASTROINTESTINAL DISORDERS; ENDOCRINAL DISEASES NOVO NORDISK A/S (DK) 1999-03-30 US disclosed