SCHEMBL847574

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16814926	0.86	MAPT (0.46)	POLBRAB9ANR4A1KMT2AMAPT
	SCHEMBL27478046	0.86	MAPT (0.46)	POLBRAB9ANR4A1KMT2AMAPT
	SCHEMBL29278468	0.85	KMT2A (0.45)	POLBRAB9ANR4A1KMT2AMAPT
	SCHEMBL848696	0.83	KMT2A (0.51)	POLBRAB9AKMT2AMAPTPKM
	SCHEMBL31128904	0.83	TDP1 (0.50)	POLBRAB9AKMT2AMAPTPKM
	SCHEMBL3026745	0.83	HSD17B10 (0.53)	POLBRAB9ANR4A1KMT2AMAPT
	SCHEMBL7659979	0.81	HTT (0.54)	RAB9AKMT2AMAPTALDH1A1HTT
	SCHEMBL31198180	0.80	POLB (0.58)	POLBRAB9ANR4A1KMT2AMAPT
	SCHEMBL7525964	0.80	TDP1 (0.52)	POLBRAB9ANR4A1KMT2AMAPT
	SCHEMBL13448607	0.79	SMN1; SMN2 (0.51)	POLBRAB9ANR4A1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.