Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816710 | 0.89 | TSHR (0.47) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL27358205 | 0.87 | AKR1C3 (0.53) | AKR1C3NPC1RAB9ANR4A1NR4A2 | |
| SCHEMBL8475788 | 0.87 | TDP1 (0.40) | ESR1ESR2AKR1C3NPC1RAB9A | |
| SCHEMBL3321749 | 0.86 | MAOB (0.50) | AKR1C3NPC1RAB9AMAPTMAOB | |
| SCHEMBL8473591 | 0.84 | LMNA (0.54) | MAPTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL10499188 | 0.84 | ESR1 (0.40) | ESR1ESR2AKR1C3NPC1RAB9A | |
| SCHEMBL10500293 | 0.83 | NPC1 (0.45) | ESR1ESR2NPC1RAB9ATDP1 | |
| SCHEMBL7805483 | 0.83 | SMN1; SMN2 (0.42) | AKR1C3NPC1RAB9ATDP1MAPT | |
| SCHEMBL3319281 | 0.82 | GSK3B (0.49) | AKR1C3NPC1RAB9ATDP1MAOB | |
| SCHEMBL7898892 | 0.81 | MEN1 (0.45) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869698-A | 1,2-dioxetane compounds as chemiluminescent labels for organic and biological molecules | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1999-02-09 | — | — | US | disclosed |
| US-5795987-A | LUMINESCENCE | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1998-08-18 | — | — | US | disclosed |
| US-5770743-A | IMMUNOASSAY | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1998-06-23 | — | — | US | disclosed |
| EP-0473984-A1 | 1,2-Dioxetane compounds as chemiluminescent labels for organic and biological molecules | THE BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1992-03-11 | — | — | EP | disclosed |