Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | HEXA | P06865 | 1/20 | 0.35 |
| ▸ | HEXB | P07686 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474773 | 0.88 | MAPT (0.38) | MAPTMAOBHEXAHEXBCCNB2 | |
| SCHEMBL8480989 | 0.88 | DPP4 (0.32) | GAAALDH1A1 | |
| SCHEMBL8578464 | 0.87 | PTGS2 (0.44) | MAOBCDK1PTGS2POLBGAA | |
| SCHEMBL8477805 | 0.87 | PDE4B (0.40) | — | |
| SCHEMBL8474810 | 0.86 | MAPT (0.37) | MAPTMAOBHEXAHEXBCCNB2 | |
| SCHEMBL8474843 | 0.80 | KDM4E (0.39) | MAPTMAOBPTGS2POLBKDM4E | |
| SCHEMBL8477582 | 0.79 | MAPT (0.38) | MAPTMAOBHEXAHEXBCCNB2 | |
| SCHEMBL8478931 | 0.78 | ESR1 (0.41) | MAPTMAOBHEXAHEXBCCNB2 | |
| SCHEMBL8474318 | 0.78 | ESR2 (0.41) | MAOBHEXAHEXBPTGS2POLB | |
| SCHEMBL8581223 | 0.77 | MAPK1 (0.36) | MAPTPTGS2GAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |