Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476167 | 0.89 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL8472040 | 0.88 | SMN1; SMN2 (0.50) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL8474407 | 0.87 | KDM4E (0.51) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL8472298 | 0.87 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL8475303 | 0.87 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL8477086 | 0.86 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL8474664 | 0.85 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL8474096 | 0.85 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL8476877 | 0.85 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL8474623 | 0.85 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |