Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476177 | 0.94 | TP53 (0.45) | ALDH1A1LMNATP53POLBAPEX1 | |
| SCHEMBL8476623 | 0.92 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDHTTKMT2A | |
| SCHEMBL8061325 | 0.91 | ALDH1A1 (0.48) | ALDH1A1LMNAPOLBTDP1HPGD | |
| SCHEMBL8471681 | 0.85 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDHTTKMT2A | |
| SCHEMBL8062389 | 0.85 | S1PR1 (0.39) | ALDH1A1LMNATP53TDP1HPGD | |
| SCHEMBL8472236 | 0.84 | ALDH1A1 (0.44) | ALDH1A1LMNATP53POLBAPEX1 | |
| SCHEMBL8473596 | 0.80 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDHTTKMT2A | |
| SCHEMBL8476555 | 0.79 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTKMT2AMAPT | |
| SCHEMBL8472203 | 0.78 | ALDH1A1 (0.54) | ALDH1A1LMNATP53TDP1HPGD | |
| SCHEMBL8471849 | 0.78 | ALDH1A1 (0.36) | ALDH1A1LMNAHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994396-A | Furansulfonic acid derivatives and pharmaceutical compositions containing the same | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-11-30 | — | — | US | disclosed |