Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477727 | 0.97 | KDM4E (0.42) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL455104 | 0.92 | KDM4E (0.36) | KDM4EMAPK1HIF1APAOXPOLB | |
| SCHEMBL7127257 | 0.86 | GAA (0.35) | KDM4EMAPK1HIF1ATDP1ALDH1A1 | |
| SCHEMBL24779728 | 0.85 | EPHX1 (0.41) | EPHX1 | |
| SCHEMBL8476029 | 0.84 | MEN1 (0.37) | KDM4EMAPK1HIF1APAOXTDP1 | |
| SCHEMBL12248067 | 0.83 | APP (0.37) | KDM4EMAPK1HIF1A | |
| SCHEMBL7129242 | 0.78 | — | — | |
| SCHEMBL7129237 | 0.78 | — | — | |
| SCHEMBL26452808 | 0.77 | PAOX (0.37) | KDM4EPAOXMEN1KMT2A | |
| SCHEMBL8474679 | 0.75 | MEN1 (0.41) | KDM4EMAPK1HIF1APAOXTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109293536-A | Chelating agent | 通用电气公司 | 2019-02-01 | — | — | CN | disclosed |
| US-5997843-A | TECHNETIUM-99M | AMERSHAM INTERNATIONAL PLC (GB) | 1999-12-07 | — | — | US | disclosed |
| WO-1995004552-A2 | RADIOMETAL COMPLEXES THAT LOCALISE IN HYPOXIC TISSUE | AMERSHAM INTERNATIONAL PLC (GB) | 1995-02-16 | — | — | WO | disclosed |