Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | FRK | P42685 | 1/20 | 0.53 |
| ▸ | CLK2 | P49760 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.53 |
| ▸ | STK3 | Q13188 | 1/20 | 0.53 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.53 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482604 | 0.85 | CYP2C9 (0.51) | ROCK2MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL8475832 | 0.83 | PIM1 (0.51) | ROCK2MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL7487055 | 0.83 | CYP2C9 (0.73) | ROCK2MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL8476895 | 0.82 | CYP2C9 (0.63) | ROCK2MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL7486197 | 0.81 | PARP1 (0.45) | ROCK2MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL8480851 | 0.81 | CYP2C9 (0.50) | ROCK2MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL8479083 | 0.81 | GSK3B (0.56) | ROCK2MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL22127114 | 0.80 | EP300 (0.49) | KDM4EALDH1A1MAP2MEN1KMT2A | |
| SCHEMBL7485354 | 0.79 | CYP2C9 (0.48) | ROCK2MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL8480726 | 0.79 | CYP2C9 (0.55) | ROCK2MAP4K4LCKCSF1RPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972961-A | ANTIISCHEMIC AGENTS; ANTICONVULSANTS; HEADACHES; SEXUAL DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-10-26 | — | — | US | disclosed |