Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | CLK2 | P49760 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.51 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.51 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.51 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.51 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.51 |
| ▸ | EEF2K | O00418 | 1/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | AKT2 | P31751 | 1/20 | 0.51 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480479 | 0.86 | CYP2C9 (0.49) | PIM1CDK2CLK2GSK3BCAMK2B | |
| SCHEMBL6545665 | 0.85 | EEF2K (0.71) | PIM1CDK2CLK2GSK3BCAMK2B | |
| SCHEMBL8482604 | 0.83 | CYP2C9 (0.51) | PIM1CDK2CLK2GSK3BCAMK2B | |
| SCHEMBL8475992 | 0.83 | ROCK2 (0.53) | PIM1CDK2CLK2GSK3BCAMK2B | |
| SCHEMBL6545659 | 0.83 | EEF2K (0.57) | PIM1CDK2CLK2GSK3BCAMK2B | |
| SCHEMBL8480710 | 0.81 | CYP2C9 (0.52) | PIM1CDK2CLK2GSK3BCAMK2B | |
| SCHEMBL8481050 | 0.81 | PIM1 (0.76) | PIM1CDK2CLK2GSK3BCAMK2B | |
| SCHEMBL8481585 | 0.80 | CYP2C9 (0.54) | PIM1CDK2CLK2GSK3BCAMK2B | |
| SCHEMBL8480726 | 0.77 | CYP2C9 (0.55) | PIM1CDK2CLK2GSK3BCAMK2B | |
| SCHEMBL7487055 | 0.76 | CYP2C9 (0.73) | PIM1CDK2CLK2GSK3BCAMK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972961-A | ANTIISCHEMIC AGENTS; ANTICONVULSANTS; HEADACHES; SEXUAL DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-10-26 | — | — | US | disclosed |