SCHEMBL8476248

SCHEMBL8476248

CCC(O)Oc1cc(C)cc(OS(=O)(=O)c2cccc(C)c2)c1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2 P00734 14/20 0.51
KMT2A Q03164 1/20 0.38
HTR6 P50406 1/20 0.37
GPR17 Q13304 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8481772 0.89 F2 (0.54) F2KMT2AHTR6
SCHEMBL8482545 0.89 F2 (0.44) F2HTR6GPR17
SCHEMBL8479180 0.89 F2 (0.44) F2GPR17
SCHEMBL8480903 0.86 F2 (0.42) F2GPR17
SCHEMBL8480407 0.83 F2 (0.54) F2KMT2A
SCHEMBL14878155 0.81 F2 (0.62) F2
SCHEMBL8482817 0.80 F2 (0.39) F2KMT2A
SCHEMBL8481378 0.80 F2 (0.56) F2
SCHEMBL8482953 0.80 F2 (0.50) F2KMT2AHTR6GPR17
SCHEMBL8481393 0.79 F2 (0.55) F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5891909-A Amidinohydrazones as protease inhibitors 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 1999-04-06 US disclosed