Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476248 | 0.83 | F2 (0.51) | F2KMT2A | |
| SCHEMBL8482545 | 0.81 | F2 (0.44) | F2 | |
| SCHEMBL8482824 | 0.81 | F2 (0.52) | F2NAPRTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8481772 | 0.81 | F2 (0.54) | F2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL8479180 | 0.81 | F2 (0.44) | F2 | |
| SCHEMBL5674314 | 0.79 | F2 (0.55) | F2NAPRTLMNAALDH1A1MAPT | |
| SCHEMBL8481901 | 0.79 | F2 (0.61) | F2LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5674366 | 0.78 | F2 (0.66) | F2 | |
| SCHEMBL8481453 | 0.78 | F2 (0.53) | F2NAPRTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8480903 | 0.78 | F2 (0.42) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891909-A | Amidinohydrazones as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |