Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.47 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | CTRC | Q99895 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477294 | 0.91 | F2 (0.57) | F2PRSS2F10CTRC | |
| SCHEMBL8481378 | 0.83 | F2 (0.56) | F2PRSS2CTRC | |
| SCHEMBL8477076 | 0.83 | F2 (0.52) | F2PRSS2F10CTRC | |
| SCHEMBL8481393 | 0.82 | F2 (0.55) | F2PRSS2F10CTRC | |
| SCHEMBL8476682 | 0.81 | F2 (0.56) | F2PRSS2F10CTRC | |
| SCHEMBL8481772 | 0.81 | F2 (0.54) | F2 | |
| SCHEMBL8479188 | 0.81 | F2 (0.56) | F2PRSS2F10CTRC | |
| SCHEMBL5674206 | 0.80 | F2 (0.60) | F2PRSS2F10CTRC | |
| SCHEMBL8482817 | 0.79 | F2 (0.39) | F2PRSS2CTRC | |
| SCHEMBL8476248 | 0.79 | F2 (0.51) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891909-A | Amidinohydrazones as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |