Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.50 |
| ▸ | PDE4A | P27815 | 5/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480648 | 0.88 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8479443 | 0.86 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8479881 | 0.85 | GAA (0.44) | PDE4BPDE4APDE4CPDE4DMAPK1 | |
| SCHEMBL8481016 | 0.81 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8478366 | 0.79 | PDE4B (0.61) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8479437 | 0.79 | GAA (0.44) | PDE4BPDE4APDE4CPDE4DMAPK1 | |
| SCHEMBL8474730 | 0.78 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL12181771 | 0.76 | PDE4B (0.71) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8475575 | 0.76 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8479030 | 0.76 | GAA (0.44) | PDE4BPDE4APDE4CPDE4DMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |