Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.61 |
| ▸ | PDE4A | P27815 | 5/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 6/20 | 0.38 |
| ▸ | MGAM | O43451 | 4/20 | 0.38 |
| ▸ | SI | P14410 | 4/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.38 |
| ▸ | HK2 | P52789 | 1/20 | 0.37 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | CREB1 | P16220 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481016 | 0.89 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DGAA | |
| SCHEMBL8479895 | 0.87 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DGAA | |
| SCHEMBL8479443 | 0.86 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8474890 | 0.81 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DGAA | |
| SCHEMBL8476378 | 0.79 | PDE4B (0.50) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8479393 | 0.79 | PDE4B (0.51) | PDE4BPDE4APDE4CPDE4DGAA | |
| SCHEMBL8480648 | 0.78 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL8482098 | 0.76 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DGAA | |
| SCHEMBL8479030 | 0.76 | GAA (0.44) | PDE4BPDE4APDE4CPDE4DGAA | |
| SCHEMBL8476950 | 0.75 | PDE4B (0.42) | PDE4BPDE4APDE4CPDE4DGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |