SCHEMBL847646

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL847645	1.00	PTH1R (0.52)	PTH1RPKLRHRH3MMP2MMP9
	SCHEMBL849474	0.92	PTH1R (0.52)	PTH1RPKLRMAPK7EPHX2CCR5
	SCHEMBL849473	0.92	PTH1R (0.52)	PTH1RPKLRMAPK7EPHX2CCR5
	SCHEMBL849797	0.92	PTH1R (0.43)	PTH1RPKLRPPARDPPARAPPARG
	SCHEMBL849796	0.92	PTH1R (0.43)	PTH1RPKLRPPARDPPARAPPARG
	SCHEMBL851096	0.89	PTH1R (0.40)	PTH1RPKLR
	SCHEMBL851095	0.89	PTH1R (0.40)	PTH1RPKLR
	SCHEMBL847546	0.88	PTH1R (0.38)	PTH1RPKLR
	SCHEMBL847545	0.88	PTH1R (0.38)	PTH1RPKLR
	SCHEMBL13064869	0.88	PTH1R (0.38)	PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.