Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 6/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.60 |
| ▸ | GRIA3 | P42263 | 6/20 | 0.60 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478909 | 0.88 | GRIA1 (0.61) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8476223 | 0.83 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8477906 | 0.81 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7980231 | 0.80 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7970099 | 0.78 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7983843 | 0.76 | GRIA1 (0.61) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL29798454 | 0.76 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL678318 | 0.76 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7984623 | 0.75 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6784577 | 0.75 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968928-A | Excitatory amino acid antagonists: fused-azacyclic quinoxalinediones and immunoassays thereof | WARNER-LAMBERT COMPANY (US) | 1999-10-19 | — | — | US | claimed |
| US-5968928-A | Excitatory amino acid antagonists: fused-azacyclic quinoxalinediones and immunoassays thereof | WARNER-LAMBERT COMPANY (US) | 1999-10-19 | — | — | US | disclosed |