Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 5/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 5/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470000 | 0.93 | KCNE1 (0.56) | KCNE1KCNQ1MAOBALDH1A1MAPT | |
| SCHEMBL7473739 | 0.92 | KCNE1 (0.52) | KCNE1KCNQ1ALDH1A1MAPTHTT | |
| SCHEMBL8476807 | 0.91 | KCNE1 (0.50) | KCNE1KCNQ1MAOBGRIN1GRIN2B | |
| SCHEMBL8483318 | 0.91 | KCNE1 (0.50) | KCNE1KCNQ1MAOBGRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL7471187 | 0.86 | KCNE1 (0.47) | KCNE1KCNQ1MAOBALDH1A1MAPT | |
| SCHEMBL6602411 | 0.85 | KCNE1 (0.56) | KCNE1KCNQ1MAOBALDH1A1MAPT | |
| SCHEMBL8481296 | 0.85 | KCNE1 (0.50) | KCNE1KCNQ1MAOBGRIN1GRIN2B | |
| SCHEMBL8476685 | 0.85 | KCNE1 (0.53) | KCNE1KCNQ1MAOBALDH1A1MAPT | |
| SCHEMBL8483181 | 0.84 | KCNE1 (0.56) | KCNE1KCNQ1MAOBALDH1A1MAPT | |
| SCHEMBL6603457 | 0.83 | KCNE1 (0.66) | KCNE1KCNQ1MAOBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955607-A | TREATING CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND (DE) | 1999-09-21 | — | — | US | disclosed |