Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.55 |
| ▸ | ALPL | P05186 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481378 | 0.84 | F2 (0.56) | F2PRSS2CTRC | |
| SCHEMBL8477294 | 0.82 | F2 (0.57) | F2PRSS2CTRC | |
| SCHEMBL8479862 | 0.82 | ALPL (0.48) | F2ALPLALPIALDH1A1POLB | |
| SCHEMBL8476926 | 0.81 | F2 (0.53) | F2ALPLALPIHPGDMEN1 | |
| SCHEMBL5674412 | 0.81 | F2 (0.57) | F2ALPLALPIHPGDMEN1 | |
| SCHEMBL8479188 | 0.81 | F2 (0.56) | F2PRSS2CTRC | |
| SCHEMBL8481393 | 0.80 | F2 (0.55) | F2PRSS2CTRC | |
| Orcinol SCHEMBL5673530 | 0.79 | F2 (0.55) | F2ALPLALPIHPGDMEN1 | |
| SCHEMBL8478438 | 0.79 | F2 (0.55) | F2PRSS2CTRC | |
| SCHEMBL8481189 | 0.79 | F2 (0.57) | F2PRSS2CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891909-A | Amidinohydrazones as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |