Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.64 |
| ▸ | CDC25B | P30305 | 2/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17919668 | 0.83 | PLK1 (0.64) | PLK1MTNR1AALDH1A1HPGDHIF1A | |
| SCHEMBL9170389 | 0.83 | GAA (0.57) | PLK1CDC25BNQO2ALDH1A1HPGD | |
| SCHEMBL11689360 | 0.81 | PLK1 (0.62) | PLK1MTNR1AALDH1A1HPGDHIF1A | |
| SCHEMBL381778 | 0.81 | PLK1 (0.67) | PLK1CDC25BMTNR1AALDH1A1HPGD | |
| SCHEMBL10909445 | 0.80 | CDC25B (0.60) | PLK1CDC25BNQO2ALDH1A1HPGD | |
| Ammonia Solution, Strong SCHEMBL9297218 | 0.80 | CDC25B (0.75) | CDC25BNQO2ALDH1A1HPGDGFER | |
| SCHEMBL9706802 | 0.80 | DEGS1 (0.60) | CDC25BALDH1A1HPGDGFERGAA | |
| SCHEMBL15591342 | 0.80 | PTGER4 (0.61) | PLK1ALDH1A1HPGDHIF1AKDM2B | |
| SCHEMBL5315678 | 0.79 | KDM4E (0.58) | CDC25BNQO2ALDH1A1HPGDKDM4E | |
| SCHEMBL19798855 | 0.79 | PLK1 (0.58) | PLK1MTNR1AALDH1A1HPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919579-A | Organic electroluminescent device | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-07-06 | — | — | US | disclosed |
| EP-0775180-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | HOECHST AG (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0775180-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005267-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-22 | — | — | WO | disclosed |
| US-4002630-A | INTERMEDIATES FOR AZO-METHINE DYES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-01-11 | — | — | US | disclosed |