SCHEMBL8477191

SCHEMBL8477191

CC(C)[Si](C(C)C)(C(C)C)n1ccc(Br)c1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28654055 0.79
SCHEMBL264536 0.70 GRM2 (0.36)
SCHEMBL4503446 0.70
SCHEMBL12234516 0.70
SCHEMBL29660466 0.69 MGAM (0.34)
SCHEMBL3928592 0.67
SCHEMBL15155025 0.67 MGAM (0.34)
SCHEMBL29937134 0.66
SCHEMBL30593763 0.66 SLC6A2 (0.30)
SCHEMBL15155026 0.66 MGAM (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5955603-A Porphyrins and porphyrin synthesis techniques TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1999-09-21 US disclosed
US-5817830-A Pyrrolic compounds TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1998-10-06 US disclosed
EP-0821686-A4 NOVEL PORPHYRINS AND PORPHYRIN SYNTHESIS TECHNIQUES UNIV PENNSYLVANIA (US) 1998-04-15 EP disclosed
EP-0821686-A1 NOVEL PORPHYRINS AND PORPHYRIN SYNTHESIS TECHNIQUES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1998-02-04 EP disclosed
WO-1996017844-A1 NOVEL PORPHYRINS AND PORPHYRIN SYNTHESIS TECHNIQUES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1996-06-13 WO disclosed