Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | STAMBP | O95630 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483322 | 0.89 | ALDH1A1 (0.40) | ALDH1A1LMNAKDM4EMAPK1HTR2C | |
| SCHEMBL6947292 | 0.79 | HTT (0.46) | ALDH1A1KDM4ECYP3A4CHRNA7CYP1A2 | |
| SCHEMBL8479651 | 0.79 | BACE1 (0.50) | ALDH1A1LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8550527 | 0.77 | BACE1 (0.48) | ALDH1A1LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8551871 | 0.77 | NAMPT (0.39) | ALDH1A1LMNAKDM4EMAPK1POLB | |
| SCHEMBL23391645 | 0.77 | BACE1 (0.45) | ALDH1A1LMNAKDM4EMAPK1CYP1A2 | |
| SCHEMBL29715998 | 0.77 | BACE1 (0.45) | ALDH1A1LMNAKDM4EMAPK1CYP1A2 | |
| SCHEMBL8549887 | 0.75 | BACE1 (0.41) | MAPK1HTR2CPOLBCYP3A4CYP1A2 | |
| SCHEMBL8482634 | 0.75 | BACE1 (0.48) | KDM4ECHRNA7SMN1; SMN2 | |
| SCHEMBL8479405 | 0.75 | NPC1 (0.44) | LMNAKDM4EPOLBCHRNA7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977105-A | Compounds | ASTRA PHARMAEUTICALS LTD. (GB) | 1999-11-02 | — | — | US | disclosed |
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |