Fluometuron

Fluometuron

SCHEMBL8477205

CN(C)C(=O)Nc1cccc(C(F)(F)F)c1.NC(=O)Nc1ccccc1

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.80
KIF11 P52732 2/20 0.64
MAPT P10636 3/20 0.62
RAB9A P51151 2/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
HTT P42858 2/20 0.62
POLB P06746 1/20 0.56
ALDH1A1 P00352 4/20 0.53
LMNA P02545 4/20 0.52
PKM P14618 1/20 0.52
PTGS1 P23219 1/20 0.51
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluometuron SCHEMBL4658882 0.91 TP53 (0.91) TP53KIF11MAPTRAB9AMEN1
Fluometuron SCHEMBL29598187 0.89 TP53 (1.00) TP53MAPTRAB9AMEN1KMT2A
Fluometuron SCHEMBL67252 0.89 TP53 (1.00) TP53MAPTRAB9AMEN1KMT2A
Fluometuron SCHEMBL1701226 0.89 TP53 (1.00) TP53MAPTRAB9AMEN1KMT2A
Fluometuron SCHEMBL28474497 0.88 TP53 (0.91) TP53MAPTRAB9AMEN1KMT2A
Fluometuron SCHEMBL28422185 0.88 TP53 (0.97) TP53MAPTRAB9AMEN1KMT2A
Fluometuron SCHEMBL19641881 0.86 TP53 (0.94) TP53MAPTRAB9AMEN1KMT2A
Fluometuron SCHEMBL28560121 0.85 TP53 (0.86) TP53MAPTRAB9AMEN1KMT2A
SCHEMBL167618 0.85 KIF11 (0.79) TP53KIF11MAPTRAB9AMEN1
Hydrochloric Acid SCHEMBL30543132 0.83 KIF11 (0.77) TP53KIF11MAPTRAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999019493-A9 CYTOCHROME P-450 CONSTRUCTS AND METHODS OF PRODUCING HERBICIDE-RESISTANT TRANSGENIC PLANTS UNIV NORTH CAROLINA STATE (US) 1999-08-05 WO disclosed
WO-1999019493-A2 CYTOCHROME P-450 CONSTRUCTS AND METHODS OF PRODUCING HERBICIDE-RESISTANT TRANSGENIC PLANTS NORTH CAROLINA STATE UNIVERSITY (US) 1999-04-22 WO disclosed