Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 7/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479145 | 0.93 | HTR2C (0.42) | GPR88NPY1RRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8473410 | 0.92 | MAPK1 (0.43) | GPR88MAPK1P2RY12NPY1RMAPT | |
| Hydrochloric Acid SCHEMBL8474178 | 0.91 | KDM4E (0.39) | GPR88MAPK1MAPTLMNAMEN1 | |
| SCHEMBL8472268 | 0.89 | MAPK1 (0.38) | GPR88MAPK1P2RY12NPY1RSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8476314 | 0.89 | KDM4E (0.38) | GPR88MAPK1LMNAMEN1KMT2A | |
| SCHEMBL8477090 | 0.89 | NPY1R (0.40) | GPR88MAPK1NPY1RMAPTSMN1; SMN2 | |
| SCHEMBL8471933 | 0.88 | MAPK1 (0.37) | GPR88MAPK1 | |
| SCHEMBL8474562 | 0.88 | MAPK1 (0.38) | GPR88MAPK1NPY1RMAPTSMN1; SMN2 | |
| SCHEMBL8475771 | 0.88 | SMN1; SMN2 (0.41) | MAPK1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL8901044 | 0.84 | NPY1R (0.41) | GPR88MAPK1NPY1RMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0777471-A1 | INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996003983-A1 | INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-15 | — | — | WO | disclosed |