Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473410 | 0.90 | MAPK1 (0.43) | MAPK1NPY1RKDM4ESMN1; SMN2GPR88 | |
| SCHEMBL8477348 | 0.89 | GPR88 (0.41) | MAPK1NPY1RSMN1; SMN2GPR88P2RY12 | |
| SCHEMBL8477090 | 0.89 | NPY1R (0.40) | MAPK1NPY1RKDM4ESMN1; SMN2GPR88 | |
| SCHEMBL8474562 | 0.85 | MAPK1 (0.38) | MAPK1NPY1RKDM4ESMN1; SMN2GPR88 | |
| SCHEMBL8472271 | 0.84 | HRH3 (0.47) | MAPK1KDM4ESMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL8901044 | 0.84 | NPY1R (0.41) | MAPK1NPY1RKDM4ESMN1; SMN2GPR88 | |
| SCHEMBL8471933 | 0.84 | MAPK1 (0.37) | MAPK1GPR88 | |
| SCHEMBL8475771 | 0.83 | SMN1; SMN2 (0.41) | MAPK1KDM4ESMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL8477078 | 0.82 | HTR2C (0.42) | MAPK1NPY1RKDM4EGPR88 | |
| SCHEMBL8479145 | 0.82 | HTR2C (0.42) | NPY1RSMN1; SMN2GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |