Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475375 | 0.99 | PTGER4 (0.50) | PTGER4KDM4ETP53TSHRMAPK1 | |
| SCHEMBL8473765 | 0.94 | PTGER4 (0.52) | PTGER4KDM4ETSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL8475515 | 0.93 | PTGER4 (0.51) | PTGER4KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8476475 | 0.92 | CNR1 (0.49) | KDM4EALDH1A1HPGDGAACNR2 | |
| SCHEMBL8474648 | 0.89 | PTGER4 (0.48) | PTGER4KDM4EALDH1A1CNR2LMNA | |
| SCHEMBL8477133 | 0.89 | PTGER4 (0.48) | PTGER4KDM4EALDH1A1CNR2LMNA | |
| SCHEMBL8474563 | 0.88 | LTA4H (0.50) | PTGER4KDM4ETP53MAPK1SMN1; SMN2 | |
| SCHEMBL8475107 | 0.87 | KDM4E (0.45) | PTGER4KDM4ETP53TSHRMAPK1 | |
| SCHEMBL8472201 | 0.86 | KDM4E (0.47) | PTGER4KDM4ETP53TSHRMAPK1 | |
| SCHEMBL8474896 | 0.86 | EGFR (0.47) | PTGER4KDM4ERAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |