Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27969023 | 0.85 | CYP1A2 (0.45) | CYP2C9CYP2C19CYP1A2CYP3A4HIF1A | |
| SCHEMBL912792 | 0.85 | CYP2C9 (0.67) | CYP2C9CYP2C19CYP1A2CYP3A4HIF1A | |
| Phosphine SCHEMBL11171774 | 0.83 | CYP2C9 (0.64) | CYP2C9CYP2C19CYP1A2CYP3A4HIF1A | |
| SCHEMBL8474675 | 0.81 | EBP (0.43) | CYP2C9CYP2C19CYP1A2CYP3A4HIF1A | |
| SCHEMBL9069470 | 0.79 | CYP2C9 (0.60) | CYP2C9CYP2C19CYP1A2CYP3A4HIF1A | |
| SCHEMBL8480984 | 0.77 | LMNA (0.44) | MEN1KMT2ASMN1; SMN2LMNAKCNH2 | |
| SCHEMBL5873436 | 0.76 | HTT (0.53) | CYP2C9CYP2C19CYP1A2CYP3A4HIF1A | |
| SCHEMBL8974025 | 0.76 | ESR1 (0.47) | CYP2C9CYP2C19CYP1A2CYP3A4HIF1A | |
| SCHEMBL5347146 | 0.76 | CYP2C9 (0.56) | CYP2C9CYP2C19CYP1A2CYP3A4HIF1A | |
| SCHEMBL8480296 | 0.76 | TAAR1 (0.42) | CYP2C9CYP2C19CYP1A2CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |
| US-4855290-A | Derivatives of quinuclidine | STATE OF ISRAEL, REPRESENTED BY PRIME MINISTER'S OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) | 1989-08-08 | — | — | US | disclosed |