Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845831 | 0.87 | TRPV1 (0.75) | TRPV1MCHR1 | |
| SCHEMBL847137 | 0.84 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL846061 | 0.84 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL846980 | 0.83 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL847641 | 0.83 | TRPV1 (0.98) | TRPV1 | |
| SCHEMBL847747 | 0.82 | TRPV1 (0.52) | TRPV1MCHR1 | |
| SCHEMBL846299 | 0.78 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL846665 | 0.77 | TRPV1 (0.72) | TRPV1 | |
| SCHEMBL847500 | 0.77 | TRPV1 (0.46) | TRPV1MCHR1 | |
| SCHEMBL847391 | 0.76 | TRPV1 (0.73) | TRPV1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603883-B1 | QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2012-03-28 | — | — | EP | claimed |