SCHEMBL847770

SCHEMBL847770

NC(=O)c1cccc(C(=O)N2c3ccccc32)c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCHE P06276 9/20 0.50
PARP1 P09874 8/20 0.50
SLC6A3 Q01959 1/20 0.50
P2RX4 Q99571 2/20 0.49
TSHR P16473 2/20 0.48
POLB P06746 1/20 0.48
CYP3A4 P08684 1/20 0.48
MAPT P10636 1/20 0.48
CYP2C19 P33261 1/20 0.48
RECQL P46063 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ACHE P22303 6/20 0.47
HPGD P15428 1/20 0.47
PARP15 Q460N3 1/20 0.44
PARP10 Q53GL7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6903165 0.87 P2RX4 (0.69) P2RX4
SCHEMBL27780509 0.86 BCHE (0.60) BCHEP2RX4TSHRACHEHPGD
SCHEMBL277339 0.82 P2RX4 (0.54) BCHEPARP1P2RX4TSHRPOLB
SCHEMBL28881466 0.82 P2RX4 (0.54) BCHEPARP1P2RX4TSHRPOLB
Terephthalamide SCHEMBL11496815 0.80 PARP1 (0.49) BCHEPARP1SLC6A3P2RX4TSHR
SCHEMBL31021028 0.79 PARP1 (0.73) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL36694 0.79 PARP1 (0.73) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL9749363 0.78 TDP1 (0.52) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL9749360 0.78 TDP1 (0.52) PARP1TSHRPOLBCYP3A4MAPT
Water SCHEMBL7768285 0.77 PARP1 (0.70) PARP1TSHRPOLBCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112824437-B Preparation method of modified polyaramide and modified polyaramide 欧美新材料(浙江)有限公司 2023-02-21 CN claimed
CN-115478439-A Porous fiber with wool-like crimped structure and preparation method thereof 东华大学 2022-12-16 CN claimed
EP-3635039-A1 POLYAMIDE MATERIAL Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) 2020-04-15 EP claimed
EP-3545005-A1 IN SITU FUNCTIONALIZATION OF POLYSACCHARIDES AND COMPOSITIONS THEREOF E. I. du Pont de Nemours and Company (US) 2019-10-02 EP claimed
WO-2018206815-A1 POLYAMIDE MATERIAL ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) (CH) 2018-11-15 WO claimed
WO-2018098068-A1 IN SITU FUNCTIONALIZATION OF POLYSACCHARIDES AND COMPOSITIONS THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2018-05-31 WO claimed
EP-3148791-A1 THERMOPLASTIC COMPOSITE LAMINATE AND ARTICLES MANUFACTURED THEREFROM E. I. du Pont de Nemours and Company (US) 2017-04-05 EP claimed
EP-2959054-A1 FIRE BARRIER Fire Protection Coatings Limited (GB) 2015-12-30 EP claimed
EP-2847436-A1 WEAR RESISTANT TURBINE FAN BLADE E. I. Du Pont de Nemours and Company (US) 2015-03-18 EP claimed
WO-2014128436-A1 FIRE BARRIER FIRE PROTECTION COATINGS LIMITED (GB) 2014-08-28 WO claimed
EP-0655096-A1 FIRE-RESISTANT MATERIAL COMPRISING A FIBERFILL BATT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-05-31 EP claimed
EP-0652986-A1 SYNTHETIC STRING FOR SPORTING APPLICATION Prince Manufacturing, Inc. (US) 1995-05-17 EP claimed
EP-0612265-A1 FILTER BAG FOR HOT GASES. DU PONT (US) 1994-08-31 EP claimed
WO-1994005841-A1 ACTIVATED CARBON-CONTAINING FIBRIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-03-17 WO claimed
WO-1994004739-A1 FIRE-RESISTANT MATERIAL COMPRISING A FIBERFILL BATT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-03-03 WO claimed
WO-1994003666-A1 SYNTHETIC STRING FOR SPORTING APPLICATION PRINCE MANUFACTURING INC. (US) 1994-02-17 WO claimed
WO-1993008896-A1 FILTER BAG FOR HOT GASES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-13 WO claimed
EP-0232757-A1 Method for treating sythetic pulp particles, and pulp particles composed of synthetic polymer TEIJIN LIMITED (JP) 1987-08-19 EP claimed
EP-0036320-B1 FILM OF AROMATIC POLYAMIDE AND PROCESS THEREFOR E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-06-20 EP claimed
EP-0061927-A1 Composite structure of an aromatic polyamide fabric coated with a fluorosilicone rubber E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-10-06 EP claimed