Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749363 | 1.00 | TDP1 (0.52) | TDP1L3MBTL1ATMPARP1MAPT | |
| SCHEMBL3105323 | 0.81 | TDP1 (0.78) | TDP1L3MBTL1ATMPARP1MAPT | |
| SCHEMBL847770 | 0.78 | BCHE (0.50) | TDP1L3MBTL1PARP1MAPTTSHR | |
| SCHEMBL27263444 | 0.75 | TDP1 (0.65) | TDP1L3MBTL1ATMPARP1MAPT | |
| SCHEMBL11493845 | 0.75 | PARP1 (0.43) | TDP1L3MBTL1PARP1MAPTTSHR | |
| SCHEMBL134024 | 0.73 | ATM (0.95) | TDP1L3MBTL1ATMMAPTCYP3A4 | |
| SCHEMBL134300 | 0.73 | ATM (0.95) | TDP1L3MBTL1ATMMAPTCYP3A4 | |
| SCHEMBL133982 | 0.73 | ATM (0.84) | TDP1L3MBTL1ATMMAPTTSHR | |
| SCHEMBL3349765 | 0.73 | ATM (0.84) | TDP1L3MBTL1ATMMAPTTSHR | |
| SCHEMBL13045507 | 0.73 | ATM (0.84) | TDP1L3MBTL1ATMMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132393-A | Wholly aromatic polyamides and copolyamides, and process therefor | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-07-21 | — | — | US | disclosed |